tag:blogger.com,1999:blog-55014633595086660772024-03-21T10:09:09.179-06:00Credible EvidenceThe title 'Credible Evidence' is a key statement to what this blog is all about primarily in the arena of Heart Disease, Cholesterol and Statins.wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.comBlogger548125tag:blogger.com,1999:blog-5501463359508666077.post-29808389536293607322018-05-14T07:53:00.000-06:002018-05-14T07:56:52.676-06:00I appreciate readers and their comments... I really do.
A note appears when you indicate that you going to comment on a post I have made which provides guidelines for you to consider as you comment and for me as I moderate those comments.
But alas those guidelines seem not to be taken seriously or perhaps they are not actually even being read by would be commenters.
I would publish more of wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com1tag:blogger.com,1999:blog-5501463359508666077.post-89679111041737183562018-02-28T06:03:00.001-07:002018-02-28T06:03:23.452-07:00
LDL Cholesterol Particle Size and Number What Gives ?
Posted on February 27, 2018
LDL Particle Size and Particle Number, What Gives?
Ron is a 72 year old retired engineer, and has a total cholesterol of 174 which hasn’t changed over the seven years we have been following him. This is quite low. Yet, Ron is concerned because his LDL particle number and LDL particle size are “outside of wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-18701617132979503212017-08-16T12:09:00.000-06:002017-08-16T12:12:30.195-06:00Why I won’t take statins for my high cholesterol - Julianne
Why I won’t take statins for my high cholesterol
In Summary, for those who took the statin for 5 years (with known heart disease):
Benefits in NNT
1 in 83 were helped (life saved)
1 in 39 were helped (preventing non-fatal heart attack)
1 in 125 were helped (preventing stroke)
Harms in NNH
1 in 100 were harmed (develop diabetes*)
1 in 10 were harmed (muscle damage)
If you have wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-3734966678052393272017-08-16T11:21:00.002-06:002017-08-16T11:21:32.588-06:00Statins in the Drinking Water? - Packer
Statins in the Drinking Water?
by Milton Packer, MedPage Today
"Universal treatment for people at minimal risk means that a physician would need to treat more than 100 patients for 10 years to obtain an extra year of good health in one person. This marginal improvement does not meet most current standards for cost-effectiveness. The benefit is so small that it disappears if qualitywmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-68432158374219885822017-06-06T07:30:00.000-06:002017-06-06T07:30:11.252-06:00The High-Cholesterol Paradox - Wainwright
The High-Cholesterol Paradox
"Being told you have ‘high
cholesterol’ is commonly taken
as a sign of an unhealthy
destiny. Research suggests that
for many elderly people the
news that they have ‘high
cholesterol’ is more often
associated with good health and
longevity .
For over 50 years this has been a
paradox, the ‘High-Cholesterol
Paradox’. What is really going
on? "
Our review found wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-3517657465993831572017-05-26T10:32:00.000-06:002017-05-26T10:33:58.857-06:00The Elderly on Primary-Prevention Statins: No Survival Gains in ALLHAT - MedscapeThe Elderly on Primary-Prevention Statins: No Survival Gains in ALLHAT
CHICAGO, IL — Statins for primary prevention do not lower the risk of death, whether cardiovascular or from any cause, when given to people aged 65 years or older with CV risk factors, suggests a secondary analysis of a major trial that caused a stir 15 years ago[1].
The ALLHAT-LLT trial had randomized >10,000 people aged wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-42913675862167940772017-05-18T08:46:00.000-06:002017-05-18T08:46:37.559-06:00Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease - GibsonEvacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease
C. Michael Gibson MD
Proud to be co-author of this New England Journal Med article showing lowering LDL does not always improve outcomes
Background
The cholesteryl ester transfer protein inhibitor evacetrapib substantially raises the wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-31273016776937849072017-05-08T07:13:00.000-06:002017-05-08T07:13:07.888-06:00It’s official, statins do not have any side effects - Kendrick
It’s official, statins do not have any side effects
"The reality is, that unless you have had a previous heart attack, statins have no effect on overall mortality. To put that another way, they don’t save lives. They don’t even prevent heart attacks or strokes in women with no previous history of heart disease.
The statistic you really want to know about statins is the following. If you wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-46186682109514328712017-04-12T14:45:00.000-06:002017-04-12T14:45:44.161-06:00
How much longer will you live if you take a statin?
"Looking at the Heart Protection Study (HPS) done in the UK, we used a technique for analysing survival time called RMST (restricted mean survival time). I won’t go into the details. The HPS study lasted for five years, and we calculated that the average increase in survival time was 15.6 days. This was at the end of five years of wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-6439976805934707722017-04-12T07:16:00.000-06:002017-04-12T07:16:38.342-06:00The effect of statins on average survival in randomised trials, an analysis of end point postponement
Malene Lopez Kristensen,
Palle Mark Christensen,
Jesper Hallas
Objective To estimate the average postponement of death in statin trials.
Primary outcome measures The average postponement of death as represented by the area between the survival curves.
Results&wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-15926598995795704262017-03-29T07:00:00.000-06:002017-03-29T07:00:18.745-06:00
Cholesterol Paradox: A Correlate Does Not a Surrogate Make
Abstract
The global campaign to lower cholesterol by diet and drugs has failed to thwart the developing pandemic of coronary heart disease around the world. Some experts believe this failure is due to the explosive rise in obesity and diabetes, but it is equally plausible that the cholesterol hypothesis, which posits that lowering wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-56192091307189895442017-02-03T08:04:00.000-07:002017-02-03T08:04:31.990-07:00The Functional Medicine Approach to High Cholesterol"The message that “cholesterol is bad and if you have high cholesterol you should take a statin to lower it” is out of date and not in sync with the most recent scientific evidence. Unfortunately, the latest findings have not trickled down to the average primary care doctor—or even the average cardiologist. Today I discuss the six underlying causes of high cholesterol and how addressing those wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-40146884061492310072017-01-10T09:51:00.000-07:002017-01-10T09:51:06.516-07:00
Study says there's no link between cholesterol and heart disease
Mon, 13 Jun 2016 12:33:00 EST
"Controversial report claims there's no link between 'bad cholesterol' and heart disease," the Daily Mail reports, while The Times states: "Bad cholesterol 'helps you live longer',".
The headlines are based on a new review which aimed to gather evidence from previous observational studies on wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-35504754638735281842016-03-10T06:42:00.000-07:002016-03-10T06:42:31.003-07:00
Thursday, 10 March 2016
Congenital abnormalities in baby born to mother using lovastatin
This study was published in the Lancet 1992 Jun 6;339(8806):1416-7 Study title and authors:Congenital abnormalities (VATER) in baby born to mother using lovastatin.
Ghidini A, Sicherer S, Willner J. This paper can be accessed at: http://www.ncbi.nlm.nih.gov/pubmed/1350826
This paper reports wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-42654807199082335952016-03-04T06:35:00.006-07:002016-03-04T06:35:38.144-07:00Sugar Consumption Plays Greater Role in Heart Disease than Saturated Fat
Science News
from research organizations
Sugar consumption plays greater role in heart disease than saturated fat
Date:
January 13, 2016
Source:
Elsevier
Summary:
Atherosclerotic Coronary Heart Disease (CHD) is responsible for one in every six deaths in the United States as well as being the leading cause of death throughout the developed world. Healthcare professionals have for many yearswmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-24342745294120558562016-02-12T11:01:00.001-07:002016-02-12T11:01:20.004-07:00The Damage Triad: Sugar, Low-Fat and Statins - glynthincs
"Many statin victims find themselves caught up in a triad of life-style damage:
Sugar,
Low-Fat and
Statin Damage
The three effects combine to cause a devastating set of circumstances which left unrecognised will lead to kidney failure, dementia and neuro-muscular damage - Life threatening, painful and debilitating conditions. General practitioners are briefed by the statin wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-70462953714761506452015-10-10T10:02:00.000-06:002015-10-10T10:02:43.122-06:00The High-Cholesterol Paradox - Wainwrighthttp://www.lizscript.co.uk/glyn/paradox.pdf
The High-Cholesterol Paradox
Based upon European WAPF Conference 2014 presentation accredited by:
The Naturopathic Nutrition Association,
Federation of Nutritional Practitioners (FNTP)
British Association of Applied Nutrition (BAAN),
British Association of Nutritional Therapy (BANT)
Glyn Wainwright MSc wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-56132331452844689362015-09-28T06:58:00.000-06:002015-09-28T06:58:18.370-06:00Why women should not take statin drugs!Several articles written by very credible doctors and researchers conclude that the risk far out weighs the benefit.
Read more here - Statins and women.
wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-35196818654992569722015-09-28T06:51:00.000-06:002015-09-28T06:51:31.699-06:00Do Statins Speed up Aging… Or Slow It? - EenfeldtDo Statins Speed up Aging… Or Slow It?
"What the researchers showed was that statin drugs make stem cells – that rejuvenate the body – divide more slowly in a test tube. This could be expected, as statins slow access to the cholesterol building blocks needed for cell division.
However, slowing the division of stem cells is not necessarily speeding up the aging process (even if it might feel wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-63127698717529280712015-09-27T16:56:00.002-06:002015-09-27T16:56:36.992-06:00Statins: Their Pleotropic Beneficial and Adverse Clinical Effects
The Impact of Statins on Biological Characteristics of Stem Cells Provides a Novel Explanation for Their Pleotropic Beneficial and Adverse Clinical Effects.
A highly interesting paper on the effects of statins on mesenchymal stem cells
Axel F Sigurdssonwmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-76906708825074395782015-09-27T15:19:00.000-06:002015-09-27T15:21:17.907-06:00
Statins may induce premature aging. Just one more reason to avoid them.
wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-79518073898553774802015-05-30T07:13:00.001-06:002015-05-30T07:13:18.510-06:00HEALTHY DIETS AND SCIENCE: A high intake of saturated fat may have protective...HEALTHY DIETS AND SCIENCE: A high intake of saturated fat may have protective...: This study was published in the Journal of Nutrition 2015 Feb;145(2):299-305 Study title and authors: Dietary intake of saturated fat...wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-58133326995422338942015-02-10T19:31:00.000-07:002015-02-10T19:33:53.463-07:00Coronary Calcium Imaging Improves on Framingham Score Regardless of Symptoms in Analysis - MedscapeCoronary Calcium Imaging Improves on Framingham Score Regardless of Symptoms in Analysis
HOUSTON, TX — In asymptomatic and symptomatic patients at low risk for coronary artery disease, the use of coronary artery calcium (CAC) imaging improves long-term prediction of risk beyond that established by the Framingham Risk Score (FRS) and exercise-treadmill and stress-perfusion testing, according wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-91960540940034339202014-11-10T08:27:00.001-07:002014-11-10T08:27:02.402-07:007 Things You Need to Know When Your Doc Says Your Cholesterol Is Too High7 Things You Need to Know When Your Doc Says Your Cholesterol Is Too Highwmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0tag:blogger.com,1999:blog-5501463359508666077.post-27417307661610689382014-10-03T13:11:00.003-06:002014-10-03T13:11:52.050-06:00The Cholesterol Myths - Ravnskov
Did you know. . .
. . . that cholesterol is not a deadly poison, but a substance vital to the cells of all mammals?
. . . that your body produces three to four times more cholesterol than you eat?
&wmodavishttp://www.blogger.com/profile/04223700681553132074noreply@blogger.com0