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Showing posts with label Low salt diet. Show all posts
Showing posts with label Low salt diet. Show all posts

Sunday, April 7, 2013

Low Salt Diet Found to Increase Mortality - Dach

Low Salt Diet Found to Increase Mortality
Part 1
by Jeffrey Dach MD

Low Salt Diet Found to Increase Mortality The Low Salt Diet Revisited

A recent Lancet study on the effect of a low salt diet made headlines, finding that a low salt diet increases mortality for patients with congestive heart failure.(1-6) The study concluded there was not enough evidence to advise a low-salt diet for the rest of us. They doubted a low salt diet would benefit the population.(6) In this article we will re-examine the low salt diet, clear away the confusion, and make recommendations about salt intake, hypertension, and health.


Health Benefits of Salt

We know from many years of published studies that increasing salt intake increases blood volume and also blood pressure. Salt is essential for maintaining blood volume, blood pressure, and overall health. The salt content of blood is similar to ocean water. Both have sodium chloride, also known as salt.

Importance of Salt

One example of the importance of salt is the common practice of starting an intravenous solution of salt and water as the first line treatment for the trauma patient upon arrival to the hospital Emergency Room.

Low Salt Diet to Reduce Blood Pressure

One of the central dogmas of mainstream medicine is the “low salt diet” as a treatment for reducing blood pressure in the hypertensive patient. Indeed, popular wisdom says that the “low salt diet” is also healthy for the rest of us “normal” people who don’t have hypertension.(25) Along with the rest of my medical school class, I was indoctrinated to believe this. Is this really true? Many studies have looked at this question. They show the “low salt diet” will in fact reduce blood pressure slightly. However, this effect is minimal, and is counteracted by compensatory mechanisms that release harmful substances into the bloodstream, hormones and chemical mediators that counteract the “low salt diet”. The released chemical mediators include insulin, epinephrine, norepinephrine, renin, aldosterone, etc. These are harmful and damaging to the vascular system. (7-11)

Low Salt Diet Increases Cardiovascular Mortality

In addition, a number of studies have found that a “low salt diet” increases cardiovascular mortality. (5) A study published in the 1995 Hypertension found 4.3 times greater mortality in hypertensive men on a low salt diet.(12) They also found higher plasma renin in these men, a hormone produced by the body which causes salt and water retention by the kidney to compensate for the low salt diet.(12-15)

A 2011 JAMA provides the reasons for this increased mortality and says … (16)
The underlying mechanisms explaining the inverse association between cardiovascular mortality and 24-hour urinary sodium excretion might be that a salt intake low enough to decrease blood pressure also increases sympathetic nerve activity, decreases insulin sensitivity, activates the renin-angiotensin system, and stimulates aldosterone secretion. (16)
A 1998 JAMA report found that a low salt diet increased plasma renin 3.6-fold and aldosterone by 3.2-fold, increases that were proportional to the degree of sodium restriction. (17) The authors also reported the “low salt diet” increased other harmful substances such as noradrenaline, cholesterol, and low-density lipoprotein cholesterol (LDL). (17) A 1999 report in American Journal of Hypertension found that “moderate salt restriction aggravates both systemic and vascular insulin resistance.” (18)
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Read the complete article here.


Low Salt Diet Part Two

In Part One, we discussed the low salt diet, and studies which show an increased mortality from a salt restricted diet. You may have been wondering about this if you saw a recent article in the New York Times by Jane Brody extolling the virtues of a low salt diet.(1) Jan Brody quotes a computer simulation model that predicted 500,000 lives saved by eliminating dietary salt in a program similar to Finland which was described in a New England Journal article.(2,3)

Gary Schwitzer does a good job on their blogs explaining where the Jane Brody article goes wrong.(4,5).

Research by Jan A. Staessen, MD, PhD, of the University of Leuven in Belgium and colleagues, raises questions regarding whether population-wide sodium restriction will actually lower cardiovascular risks. (5,6) In actually clinical studies where 24 hr sodium excretion is measured in 3681 participants and followed over 8 years, this is what they found:

In this population-based cohort, systolic blood pressure, but not diastolic pressure, changes over time aligned with change in sodium excretion, but this association did not translate into a higher risk of hypertension or CVD complications. Lower sodium excretion was associated with higher CVD mortality.(5,6)
 
This type of data seems to suggest that salt restriction has been over-hyped as an intervention, and although will help to slightly reduce blood pressure, does not reduce mortality or complications of cardiovascular disease.

I would agree with Jane Brody that hypertension, heart disease and other health problems are a direct result of diets containing large amounts of processed salt (NaCl), Trans Fats, Sugars, MSG, Aspartame, GMO corn and GMO Soy, and added wheat fillers. To focus attention on the salt content alone, while ignoring the other harmful additives may be not be a valid exercise.

The “low salt diet” for reducing blood pressure in the hypertensive patient is a central dogma of mainstream medicine. Indeed, popular wisdom says that the “low salt diet” is also healthy for the rest of us “normal” people who don’t have hypertension. Along with the rest of my medical school class, I was indoctrinated to believe this. Is this really true? Many studies have looked at this question. They show the “low salt diet” will in fact reduce blood pressure slightly. However, this effect is minimal, and is counteracted by compensatory mechanisms that release harmful substances into the bloodstream, that counteract the “low salt diet”. The released chemical mediators include insulin, epinephrine, norepinephrine, renin, aldosterone, etc. These are harmful and damaging to the vascular system.

In addition, a number of studies have found that a “low salt diet” increases cardiovascular mortality. A study published in the 1995 Hypertension found 4 times greater mortality in hypertensive men on a low salt diet.
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Read the complete article here.

This new link added April 30, 2013: WebMD offers dangerous junk science-based dietary salt advice… This article states that "… even though one of its cited “experts” tacitly admits there is no established cause-and-effect relationship between typical/normal/current salt intake and adverse health effects."

Another article from Food Politics by Marion Nestle found here and

here: http://news.nationalpost.com/2013/09/22/little-evidence-sharp-reductions-in-salt-consumption-will-improve-health-heart-researcher-says/

More data in the Salt Wars - Aug 14, 2014; http://www.medpagetoday.com/Cardiology/Hypertension/47203

An article by Marion Nestle - http://www.foodpolitics.com/2014/08/its-salt-arguments-again-new-research-arguments-over-public-health-recommendations-and-issues-of-conflicts-of-interest/

Monday, December 10, 2012

Scant Evidence That Salt Raises BP - Kaiser

Scant Evidence That Salt Raises BP, Review Finds

The evidence for health benefits associated with salt reduction is controversial and the "concealment of scientific uncertainty" is a mistake, researchers suggested.

Controversy about what effect too much sodium intake has on the body goes back to the early part of the 20th century, according to Ronald Bayer, PhD, and colleagues from Columbia University Mailman School of Public Health in New York City.

But in the last few years, the discourse has reached a fever pitch, they wrote online in Health Affairs.

In 2011, for example, the Journal of the American Medical Association published a study by Stolarz-Skrzypek et al. that found only a weak correlation between salt and blood pressure. An editorial in the Lancet lambasted the JAMA study as "disappointingly weak" and "likely to confuse public perceptions of the importance of salt as a risk factor for high blood pressure, heart disease, and stroke."

Also in 2011, the Cochrane Review published two studies finding little or no relationship with all-cause mortality and salt reduction. The Lancet criticized both the Cochrane Library and the authors, saying, "They have seriously misled the press and thereby the public."

One of those reviews had concluded that "after more than 150 randomized controlled trials and 13 population studies without an obvious signal in favor of sodium reduction, another position could be to accept that such a signal may not exist."

Bayer and colleagues cited several studies that could not find a link between salt intake and elevated blood pressure, including a 1967 study of the Framingham cohort, and Japanese and Scottish reports in the 1980s totalling 15,000 people that concluded the association between sodium and blood pressure is "extremely weak."

The researchers noted that most of the evidence pointed to the weakest of correlations between salt and blood pressure. Yet, the cause to reduce salt was taken up by government agencies with special speed.

They cited a 2010 Institute of Medicine report called "Strategies to Reduce Sodium Intake in the United States." In the report, the IOM claimed that the "harmful relationship of salt with hypertension has been known for 40 years," which Bayer and colleagues argue is debatable -- based on the evidence.

"The [IOM] report was welcomed by the incoming president of the the American Society of Hypertension," the investigators wrote, "who warned that the 'outcomes mafia' might challenge the justification for a regulatory approach."

In 2011, the FDA also called for data and recommendations "that would help it shape regulatory policy on salt in food."

"All the while, skeptics still were asking for the evidence," Bayer and colleagues wrote.
More than 20 years prior to the IOM report, C. Everett Koop, MD, the U.S. Surgeon General, issued a report noting that government agencies were "very quick to embrace the importance of salt reduction in the 1970s and 1980s, which stood in stark contrast for the snail's pace of recommendations related to reducing blood cholesterol levels."

The authors cited many more studies finding little association between salt and blood pressure that did not eliminate the stigma attached to the mineral.

Advocates for salt reduction questioned the science behind studies that didn't conform to their opinion, and proponents partially blamed the food industry because it was in their best interest to muddy the waters and keep the debate going.

One of the interesting things about this debate, Bayer and colleagues pointed out, was that you could find respected academics on both sides.

"At the most fundamental level, we believe that it is essential to recognize the role that judgment and values must play in evidence-informed policy making," the authors concluded.

"Science must remain open, skeptical, and concerned about unmeasured confounding and selection bias in studies that accompany even the best efforts to articulate the evidence for new interventions," they added.

The investigators said that one of the reviewers of this paper had asked, "In the end, does the harm of exaggerating certainty do more harm than good? After all, it would be very hard to make any policy from a position of informed, complicated, contextualized ambivalence."

They concluded that the "concealment of scientific uncertainty is a mistake that serves neither the ends of science nor good policy. Simplistic pictures of translation from evidence to action distort our ability to understand how policy is, in fact, made and how it should be made."
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Read the complete article here.

Another article here.

More data in the Salt Wars - Aug 14, 2014; http://www.medpagetoday.com/Cardiology/Hypertension/47203

An article by Marion Nestle - http://www.foodpolitics.com/2014/08/its-salt-arguments-again-new-research-arguments-over-public-health-recommendations-and-issues-of-conflicts-of-interest/

Friday, July 22, 2011

Low Salt Diet Increases Cardiovascular Mortality

Read the full article with links and references here.

 
Another article here.

More data in the Salt Wars - Aug 14, 2014; http://www.medpagetoday.com/Cardiology/Hypertension/47203
 
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Low Salt Diet Increases Cardiovascular Mortality by Jeffrey Dach MD

from Jeffrey Dach MD Bio-Identical Hormone Blog

Hypertension Low Salt Natural Sea Salt Jeffrey DachLow Salt Diet Found to Increase Mortality
by Jeffrey Dach MD

The Low Salt Diet Revisited

A recent study on the effect of a low salt diet made headlines, finding that a low salt diet increases mortality for patients with congestive heart failure.(1-6) The study concluded there was not enough evidence to advise a low-salt diet for the rest of us. They doubted a low salt diet would benefit the population.(6) In this article we will re-examine the low salt diet, clear away the confusion, and make recommendations about salt intake, hypertension, and health.

Above left image, harvesting sea salt courtesy of wikimedia commons. (Salt Farmers - Pak Thale.jpg)


Health Benefits of Salt
We know from many years of published studies that increasing salt intake increases blood volume and also blood pressure. Salt is essential for maintaining blood volume, blood pressure, and overall health. The salt content of blood is similar to ocean water. Both have sodium chloride, also known as salt.

Importance of Salt

One example of the importance of salt is the common practice of starting an intravenous solution of salt and water as the first line treatment for the trauma patient upon arrival to the hospital Emergency Room.

Low Salt Diet to Reduce Blood Pressure

One of the central dogmas of mainstream medicine is the "low salt diet" as a treatment for reducing blood pressure in the hypertensive patient. Indeed, popular wisdom says that the "low salt diet" is also healthy for the rest of us "normal" people who don't have hypertension.(25) Along with the rest of my medical school class, I was indoctrinated to believe this. Is this really true? Many studies have looked at this question. They show the "low salt diet" will in fact reduce blood pressure slightly. However, this effect is minimal, and is counteracted by compensatory mechanisms that release harmful substances into the bloodstream, hormones and chemical mediators that counteract the "low salt diet". The released chemical mediators include insulin, epinephrine, norepinephrine, renin, aldosterone, etc. These are harmful and damaging to the vascular system. (7-11)

Low Salt Diet Increases Cardiovascular Mortality

In addition, a number of studies have found that a "low salt diet" increases cardiovascular mortality. (5) A study published in the 1995 Hypertension found 4.3 times greater mortality in hypertensive men on a low salt diet.(12) They also found higher plasma renin in these men, a hormone produced by the body which causes salt and water retention by the kidney to compensate for the low salt diet.(12-15)
A 2011 JAMA provides the reasons for this increased mortality and says ... (16)

The underlying mechanisms explaining the inverse association between cardiovascular mortality and 24-hour urinary sodium excretion might be that a salt intake low enough to decrease blood pressure also increases sympathetic nerve activity, decreases insulin sensitivity, activates the renin-angiotensin system, and stimulates aldosterone secretion. (16)

A 1998 JAMA report found that a low salt diet increased plasma renin 3.6-fold and aldosterone by 3.2-fold, increases that were proportional to the degree of sodium restriction. (17) The authors also reported the "low salt diet" increased other harmful substances such as noradrenaline, cholesterol, and low-density lipoprotein cholesterol (LDL). (17) A 1999 report in American Journal of Hypertension found that "moderate salt restriction aggravates both systemic and vascular insulin resistance." (18)
The Difference Between Refined Salt and Natural Sea Salt

In his book, Salt Your Way to Health, Dr. David Brownstein points out the difference between Refined Salt, commonly used in all processed foods, and Natural Sea Salt.(21) White refined salt is processed so that all the trace minerals are removed, and instead has chemicals added (up to 2% of weight). The added chemicals are ferrocyanide, aluminum, ammonium citrate, etc and are used for anti-caking, free-flowing, and to prolong shelf life. The final result is a lifeless, unnatural salt product which tends to acidify the body also called refined salt. Natural Sea Salt, on the other hand, retains all the trace minerals naturally found in the ocean. In addition it alkalinizes the body and has many health benefits. Natural Sea Salt is made by evaporating ocean water, and then collecting or harvesting the salt.

Popular brands of natural sea salt include:

1) Celtic Sea Salt®, Light Grey, By The Grain & Salt Society, Coarse Ground, 1 lb

2) Roland Fine Sea Salt, 27.8-Pound Package (See all Sea Salt)


Case reports from Dr Brownstein's Natural Ocean Sea Salt Book

Case Number One- Food Allergies (from the Salt book) 61 year old female with numerous allergies. The patient switched from refined salt to natural sea salt, measured urine and saliva pH, which went up (alkaline) and noted allergies resolved.

Case Number Two-Male Hypertension on Meds, Jack 63 year old hypertensive on two BP meds, Dyazide and Lopressor causing fatigue and erectile dysfunction. He switched from a low salt diet to natural sea salt and two months later blood pressure was lower. Pt reduced BP meds to dyazide at half dose.

Case three, Barbara -Hypertension, 53 y/o went to primary care doctor for check up and was shocked to find her BP was 165/100. She had been on a low salt diet for years. Blood tests showed a low sodium level (137). She was then placed on natural sea salt, half tsp per day, and vitamin-mineral regimen, and eliminated refined foods.
Two months later her blood pressure was 110/70, and she felt better.

Case Four Sandra, similar story to Barbara.

Case Five, Seizure Disorder.
Jerry 12 years old with recurrent seizures on meds.Sodium was 138 on low salt diet. Switched to natural sea salt. Seizures decreased by 50%.

Case Six Migraines. Lisa 31 , three migraines per month, clinically dehydrated, low sodium 139. Instructed to take half tsp Celtic Sea Salt per day, and 2 liters of water per day. Migraine headaches disappeared.

Case Seven- Fibromyalgia . Judy 35 y/o , five years with fibromyalgia. BP drops upon standing. Adrenal Fatigue. RX adrenal hormones (DHEA, cortisol, pregnenolone, testosterone, progesterone ) , and natural sea salt., whole foods, plentiful water. Immediate improvement.

Clinical Uses of Natural Sea Salt

Adrenal Exhaustion:
Sea Salt is essential for treatment of adrenal fatigue.
Diabetes, Elevated Blood Sugar-
It is impossible to control blood sugar on a "low salt diet". These do well on sea salt.
Muscle Cramps -
often relieved by minerals in Sea Salt.
Osteoporosis Treatment
requires minerals found in Sea Salt
Hypertension-
Low salt diet causes increased mortality. Use natural sea salt, with reduction in blood pressure noted in any cases.

How to Reduce Blood Pressure Naturally -Salt Substitutes
The low sodium, high potassium, high magnesium salt substitute (26)

A number of studies have looked at substituting table salt with a variant with reduced sodium, and increased potassium, and magnesium, which has shown to reduce blood pressure. (26) Magnesium alone is an excellent mineral supplement which may be effective for blood pressure control in hypertensive patients.(27)

Salt Substitute From Finland

Jonathan Wright's clinic offers a salt substitute which contains potassium, magnesium, and lysine which was found beneficial in a Finland.(28)(29)
WrightSalt is available through the Tahoma Clinic Dispensary (www.tahomadispensary.com 888-893-6878 ), or Ayush Herbs (800-925-1371),

L-Arginine and the ADMA Connection

In 1998 the Nobel Prize in Medicine was awarded to Furchgott and colleagues for the discovery of the role of Nitric Oxide in blood pressure regulation (among other things). (29-31) Recently, a new test has been devised called the ADMA from Metametrix Labs which is useful in hypertensive patients, showing the ability (or inability) to manufacture Nitric Oxide. If ADMA is found to be high, indicating low Nitric Oxide production, then increases can be achieved with a simple amino acid supplement called L-Arginine. (29-31) The increased Nitric Oxide brings down and controls blood pressure.(32) The references for the ADMA test can be found here.

No Iodine Added to Natural Sea Salt

Remember, Natural Sea Salt does not contain added iodine, so it is important to test for iodine levels, and supplement with iodine if found low. Iodine supplementation is our most important means for breast cancer prevention.

Credit and thanks goes to the book, Salt Your Way to Health, by David Brownstein MD for much of the information in this article.

Jeffrey Dach MD
7450 Griffin Suite 190
Davie Florida
954 792-4663