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Showing posts with label magnesium. Show all posts
Showing posts with label magnesium. Show all posts

Wednesday, August 1, 2012

Magnificent Magnesium - Czapp


Magnificent Magnesium

Written by Katherine Czapp  
September 23 2010

The Neglected Mineral We Cannot Live Without





Magnesium is an alkaline earth metal, the eighth most abundant mineral found in the earth’s crust. Because of its ready solubility in water, magnesium is the third most abundant mineral in sea water, after sodium and chloride. In the human body, magnesium is the eleventh most plentiful element by mass—measuring about two ounces. Most magnesium contained in the body is found in the skeleton and teeth—at least 60 to 65 percent of the total. Nearly the entire remaining amount resides in muscle tissues and cells, while only one percent is contained in our blood.

The importance of magnesium ions for all life itself, as well as for overall vibrant health, is hard to overstate. Magnesium is required to give the “spark of life” to metabolic functions involving the creation of energy and its transport (ATP, the body’s fundamental energy currency), and the creation of proteins—the nucleic acid chemistry of life—RNA and DNA, in all known living organisms. In plants, a magnesium ion is found at the center of every chlorophyll molecule, vital for the creation of energy from sunlight. Magnesium is an essential element for both animals and plants, involved in literally hundreds of enzymatic reactions affecting virtually all aspects of life.

Every single cell in the human body demands adequate magnesium to function, or it will perish. Strong bones and teeth, balanced hormones, a healthy nervous and cardiovascular system, well-functioning detoxification pathways and much more depend upon cellular magnesium sufficiency. Soft tissue containing the highest concentrations of magnesium in the body include the brain and the heart—two organs that produce a large amount of electrical activity, and which can be especially vulnerable to magnesium insufficiency.

Magnesium works in concert with calcium to regulate electrical impulses in the cell—magnesium concentration inside healthy cells is ten thousand times greater than calcium, and there are crucial reasons for this safeguard. Cellular calcium channels allow that mineral to enter the cell only as long as needed to conduct an impulse; it is ushered out immediately by magnesium once its task is fulfilled. This vigilance is necessary to prevent calcium accumulation in the cell, which could cause dangerous hyper-excitability, calcification, cell dysfunction and even cell death. When excess calcium enters the cells because of insufficient magnesium, muscle contraction is sustained for too long, and we suffer, for example, twitches and tics in mild cases. When magnesium deficiency becomes chronic, we suffer the symptoms of heart disease such as angina pectoris, hypertension and arrhythmia, or the spasms and contractions characteristic of asthma, migraine headache or painful menstrual cramping.

Magnesium operates as a natural calcium channel blocker and is responsible for relaxation—counter to calcium’s contraction. Thus magnesium is pivotally important to the healthy functioning of our parasympathetic nervous system. It may be hard to believe, but our bodies were actually designed to operate for the most part in a calm, relaxed parasympathetic state, rather than in the heart-pounding, stress- and adrenaline-driven mode of sympathetic nervous system dominance that is nearly constant for many of us today, and which uses up great quantities of magnesium.

Magnesium is so important to so many vital body functions, and its deficiency is integrally involved in so many diseases, that more than one researcher has dubbed magnesium a miracle in its ability to resolve or improve numerous disorders. The current list of disorders with direct and confirmed relationships to chronic and acute magnesium deficiency is long, and includes many diseases whose conventional medical treatment does not commonly address magnesium insufficiency (see below). Ongoing research promises to uncover further associations between magnesium deficiency and other illnesses.

MAGNESIUM DEFICIENCY IS ENDEMIC

Unfortunately, it is difficult to reliably supply our bodies with sufficient magnesium, even from a good, balanced whole foods diet. First of all, modern agricultural methods favor the universal use of NPK fertilizers (nitrogen, phosphorus, and potassium). Both potassium and phosphorus are antagonists of magnesium in the soil, and on calcareous soils create a relative magnesium deficiency (the magnesium present is bound and therefore unavailable to the crop). On sandy or loamy soils that are slightly acid, an actual magnesium deficiency often exists, as the magnesium leaches from the soil and is also unavailable to the crop. This leaching also occurs in response to acid rain.

Magnesium, in fact, is one of the most depleted minerals in farm soils. To add insult to injury, new plant hybrids are continually introduced that have been bred to survive on these mineral-depleted soils. Of course, when mineral-depleted crops are eaten by animals or by us, they will sooner or later cause disease. Even though organically raised crops should be a better bet nutritionally, this isn’t always the case, and it pays in terms of your health to learn how your farmer replenishes the minerals on his fields.

“Do you know that most of us today are suffering from certain dangerous diet deficiencies which cannot be remedied until depleted soils from which our food comes are brought back into proper mineral balance? The alarming fact is that foods (fruits, vegetables, grains) now being raised on millions of acres of land that no longer contain enough of certain minerals are starving us—no matter how much of them we eat. The truth is that our foods vary enormously in value, and some of them aren’t worth eating as food.” These words of warning are from the 74th Congress, 2nd session, Senate document number 264, of 1936. It is truly sobering to learn that the decline in soil mineral balance was a topic of serious national concern more than seventy years ago, and the deficit has been affecting us—while steadily getting worse— since our grandparents’ generation.

Magnesium and other nutrients are diminished or lost in produce after harvest, through handling, refrigeration, transport and storage, even if all these steps were done “properly.” Buying produce and then storing it for days in your own refrigerator continues the nutrient loss, whether the produce is from the supermarket or your local farmers’ market.

Food processing causes enormous loss of magnesium in foods that are commonly fairly good sources of it, such as leafy greens, nuts, seeds and whole grains. Most of the magnesium in grain— found in the bran and germ—is lost in milling whole grains for white flour, which is used nearly exclusively for hundreds of devitalized processed food items. When nuts and seeds are roasted or their oils extracted, magnesium is lost. Cooking greens causes whatever magnesium they might contain to leach into the cooking water. Foods tend to lose less calcium than magnesium through these processes, adding to a troublesome dietary calcium overload that we will discuss shortly.
Fluoride in drinking water binds with magnesium, creating a nearly insoluble mineral compound that ends up deposited in the bones, where its brittleness increases the risk of fractures. Water, in fact, could be an excellent source of magnesium—if it comes from deep wells that have magnesium at their source, or from mineral-rich glacial runoff. Urban sources of drinking water are usually from surface water, such as rivers and streams, which are low in magnesium. Even many bottled mineral waters are quite low in magnesium, or have a very high concentration of calcium, or both.
A diet of processed, synthetic foods, high sugar content, alcohol and soda drinks all “waste” magnesium, as a lot of it is required for the metabolism and detoxification of these largely fake foods. According to Dr. Natasha Campbell-McBride, the body requires at least twenty-eight molecules of magnesium to metabolize a single molecule of glucose. Phosphates in carbonated drinks and processed meats (so-called “luncheon meats” and hot dogs) bind with magnesium to create the insoluble magnesium phosphate, which is unusable by the body.

Tannins, oxalates, and phytic acid all bind with magnesium, making it unavailable to the body unless extra care is taken to neutralize some of these compounds during food preparation. It is interesting to note that foods commonly containing magnesium (provided they were grown in mineral-rich soil) also contain lots of these anti-nutrients, such as spinach (oxalates) and whole grains (phytates).

Many commonly prescribed pharmaceutical drugs cause the body to lose magnesium via the urine, such as diuretics for hypertension; birth control pills; insulin; digitalis; tetracycline and some other antibiotics; and corticosteroids and bronchodilators for asthma. With the loss of magnesium, all of the symptoms being “treated” by these drugs over time inevitably become worse.

Magnesium absorption is impeded with the use of supplemental iron. If you take calcium supplements, your need for magnesium increases, and in fact calcium will not be properly absorbed or metabolized if adequate magnesium is missing, and will mostly end up dangerously deposited in soft tissues. Magnesium is responsible for converting vitamin D to the active form that allows calcium to be absorbed, and also regulates calcium’s transport to hard tissues where it belongs.

Lactose is another inhibitor of magnesium absorption (and milk is not a good source of the mineral to begin with), along with excess potassium, phosphorus and sodium.

Mental and physical stress, with its related continuous flow of adrenaline, uses up magnesium rapidly, as adrenaline affects heart rate, blood pressure, vascular constriction and muscle contraction— actions that all demand steady supplies of magnesium for smooth function. The nervous system depends upon sufficient magnesium for its calming effects, including restful sleep. Hibernating animals, by the way, maintain very high levels of magnesium. Magnesium deficiency will accelerate a vicious cycle and amplify the effects of chronic stress, leading to more anxiety, irritability, fatigue and insomnia—many of the symptoms of adrenal exhaustion—as well as to hypertension and heart pains—symptoms of heart disease.

Depression is related to stress and magnesium deficiency as well. Serotonin, the “feel good” hormone, requires magnesium in its delicate balance of release and reception by cells in the brain. Only when adequate levels are present can we enjoy mental and emotional equilibrium.

For reasons not fully understood, the body does not retain magnesium very well; certainly not as well as it holds onto calcium or iron, for example. Heavy sweating from endurance sports such as marathon running or strenuous exercise workouts can dangerously deplete magnesium stores and other electrolytes—although calcium is not wasted, by the way— resulting in trembling, faintness and even seizures and death. The drenching sweats that some menopausal women suffer cause magnesium loss as well, and their diminishing magnesium levels worsen their jagged nerves, sleep disturbances, panic attacks, body aches and depression. If these women have been tempted to consume modern soy products in a misguided attempt to moderate their symptoms, they will in fact lose even more magnesium because it will be bound to the abundant phytates in these concoctions.
A healthy gut environment is necessary for proper absorption of magnesium from the diet. Irritable bowel syndrome, leaky gut, candidiasis and other gut disorders can severely limit the amount of magnesium that the body will be able to absorb. Older adults often experience decreased stomach hydrochloric acid production, which can impair mineral absorption in general. And with so many treating their “heartburn” with antacids, a healthy digestive environment is hard to maintain.

CALCIUM AND MAGNESIUM PARTNERSHIP

Both calcium and magnesium are necessary for the healthy body—in proper balance to one another, as well as to other necessary minerals. Considered biochemical antagonists, one cannot act without eliciting the opposite reaction of the other. Yet calcium and magnesium must both be present in balanced amounts for either one to function normally in the body. Some researchers suggest that the healthy ratio of calcium to magnesium in the diet should be 2:1. Others consider 1:1 to reflect ratios that we evolved with based on our diet prior to the advent of agriculture. In modern industrialized countries the ratio from diet is from 5:1 to as much as 15:1. The imbalance of these two very important minerals produces many dire consequences in the body that are often overlooked by medical practitioners when treating the disease states they cause.

Aside from the intricate electrical dance that calcium and magnesium perform together, magnesium is necessary to keep calcium in solution in the body, preventing its inappropriate deposition in soft tissues. As long as we have sufficient hydrochloric acid in our stomachs we can dissolve calcium from the foods we eat. After calcium leaves the acidic environment of the stomach and enters the alkaline milieu of the small intestine however, it is magnesium that is necessary to keep calcium soluble. Without sufficient magnesium, a whole host of physiological aberrations can occur with serious health consequences.

As Dr. Carolyn Dean, author of The Magnesium Miracle, explains, “In the large intestine it [precipitated calcium] interferes with peristalsis, which results in constipation. When calcium precipitates out in the kidneys and combines with phosphorus or oxalic acid, kidney stones are formed. Calcium can deposit in the lining of the bladder and prevent it from fully relaxing, and therefore from filling completely with urine. This leads to frequent urination problems, especially in older people. Calcium can precipitate out of the blood and deposit in the lining of the arteries, causing hardening (arteriosclerosis). . . It can coat and stiffen. . . plaque in the arteries. . . [and] can cause blood pressure to rise as well as increase the risk of heart attack and stroke. Calcium can even deposit in the brain. Many researchers are investigating it as a possible cause of dementia, Alzheimer’s and Parkinson’s disease. Calcium can deposit in the lining of the bronchial tubes and cause asthma symptoms. Calcium in extracellular fluid. . . can decrease the permeability of cell membranes. This makes it increasingly difficult for glucose (a large molecule) to pass through the cell membrane to be converted to ATP in the cells’ mitochondria. High glucose levels created by excess calcium may be misdiagnosed as diabetes.”

MAGNESIUM IS A POTENT DETOXIFIER

Magnesium is utilized by the body for all sorts of detoxification pathways and is necessary for the neutralization of toxins, overly acidic conditions that arise in the body, and for protection from heavy metals. It plays a vital role in protecting us from the onslaught of man-made chemicals all around us. Glutathione, an antioxidant normally produced by the body and a detoxifier of mercury, lead and arsenic among others, requires magnesium for its synthesis. According to Mark Sircus, in Transdermal Magnesium Therapy, a deficiency of magnesium increases free radical generation in the body and “causes glutathione loss, which is not affordable because glutathione helps to defend the body against damage from cigarette smoking, exposure to radiation, cancer chemotherapy, and toxins such as alcohol and just about everything else.”

When our bodies are replete with magnesium (and in balance with the other essential minerals) we are protected from heavy metal deposition and the development of associated neurological diseases. As Dr. Carolyn Dean explains, “Research indicates that ample magnesium will protect brain cells from the damaging effects of aluminum, beryllium, cadmium, lead, mercury and nickel. We also know that low levels of brain magnesium contribute to the deposition of heavy metals in the brain that heralds Parkinson’s and Alzheimer’s. It appears that the metals compete with magnesium for entry into the brain cells. If magnesium is low, metals gain access much more readily.

“There is also competition in the small intestine for absorption of minerals. If there is enough magnesium, aluminum won’t be absorbed.”

MAGNESIUM DEFICIENCY IN TOOTH DECAY AND OSTEOPOROSIS

Ask anyone—your neighbor or even your dentist or doctor—what bones and teeth require to be strong and healthy, and you will undoubtedly hear the response, “Plenty of calcium.” Bones and teeth certainly do require calcium—as well as phosphorus and magnesium, but without adequate amounts of the latter, calcium will not be deposited in these hard tissues, and the structures will not be sound. “When you load up your system with excess calcium,” writes William Quesnell, in Minerals: the Essential Link to Health, “you shut down magnesium’s ability to activate thyrocalcitonin, a hormone that under normal circumstances would send calcium to your bones.” Instead of providing benefits to the body, the displaced calcium actually becomes toxic, causing trouble in soft tissues of the kinds we’ve already discussed.

Numerous studies, in fact, have established the fact that it is dietary magnesium, not calcium, (and certainly not fluoride) that creates glassy hard tooth enamel that resists decay, and strong and resilient bones. Regardless of the amount of calcium you consume, your teeth can only form hard enamel if magnesium is available in sufficient quantities.
According to J. I. Rodale, in Magnesium: the Nutrient that Could Change Your Life, “For years it was believed that high intakes of calcium and phosphorus inhibited decay by strengthening the enamel. Recent evidence, however, indicates that an increase in these two elements is useless unless we increase our magnesium intake at the same time. It has even been observed that dental structures beneath the surface can dissolve when additional amounts of calcium and phosphorus diffuse through the enamel at different rates. Thus milk, poor in magnesium, but high in the other two elements, not only interferes with magnesium metabolism, but also antagonizes the mineral responsible for decay prevention.”

To revisit Deaf Smith County, Texas, and the justly famous residents whose teeth refused to succumb to decay, Rodale quotes the observations of Dr. Lewis Barnett, presented in a paper before the Texas Medical Association in Dallas, 1952. Dr. Barnett, an orthopedic surgeon, remarked on the low incidence of tooth decay and rapid healing of broken bones among these residents, and offered this explanation: “[The local] water and foods have a very high magnesium and iodine content and recently we have proven that all of the trace minerals known to be essential are present in the water and foods grown in that area.” Further, Dr. Barnett had found that the magnesium bone content of the average Deaf Smith County resident was up to five times higher than that of a resident of Dallas, while the concentrations of calcium and phosphorus were about the same in both groups. His observations led him to state that “[o]ne of the most important aspects of the disease osteoporosis has been almost totally overlooked. That aspect is the role played by magnesium.”

Rodale emphasizes the fact that Dr. Barnett gave much of the credit for these health benefits to the high magnesium content of the local water, and noted many signs of superior bone development among people in the area: “Dr. Barnett makes mention of the fact that people in older years frequently have fracture of the cervical neck of the femur and these are very difficult to heal in many localities. However, he noted that this fracture rarely occurs in Deaf Smith County, whereas it was common in Dallas County, Texas, where he also practiced. When a fracture did occur in Deaf Smith, healing was easy and rapid even in people eighty to one hundred years old. In contrast, fractures in Dallas were common and very difficult to heal, if not impossible.”

Over fifty years ago Dr. Barnett tested the magnesium levels of five thousand people and found sixty percent of them to be deficient. How much more of the population is deficient today, when all of the negative conditions contributing to that deficiency have been certainly amplified?

FOOD SOURCES OF MAGNESIUM

As we’ve mentioned, if farm soils are well-mineralized, leafy green vegetables, seeds, tree nuts and whole grains are fairly good sources of magnesium. Certain wild-crafted forage foods really stand out, however, such as nettles (860 mg per 100 grams) and chickweed (529 mg per 100 grams), and add many tonic and nutritive benefits to both human and livestock diets largely due to their high mineral content. Kelp, ancient denizen of the sea, contains spectacular levels, as do most sea vegetables. Remember that they are continually bathed in a solution whose third most abundant mineral is magnesium. And authentic, unrefined sea salt is a very good source of magnesium, along with trace minerals. Utilizing bone broths on a daily basis will provide another excellent source of minerals, including magnesium, in a highly assimilable form.

STRATEGIES FOR MAGNESIUM SUPPLEMENTATION

Even with ideal digestive conditions, only a percentage of magnesium in foods will be absorbed—less when amounts in the body are adequate and more if there is a deficiency. This is also true of magnesium supplements, and there are many of them on the market to confuse you. For the average person, magnesium supplementation is safe to experiment with on your own, especially if you know you have symptoms that could be related to magnesium deficiency or are under extra stress, and so on. Excess magnesium is excreted in urine and the stool, and the most common response to too much magnesium is loose stools. Those with renal insufficiency or kidney disease, extremely slow heart rate, or bowel obstruction should avoid magnesium therapy.

General dosage recommendations range from about 3 to 10 milligrams per pound of body weight, depending upon physical condition, requirements for growth (as in children), and degree of symptoms.

Oral magnesium supplements are available in organic salt chelates, such as magnesium citrate and magnesium malate. These are fairly well absorbed, especially in powder forms to which you add water and can tailor your dosage. It is important to divide your dosage during the day so that you do not load your body with too much magnesium in any single dose. Carolyn Dean recommends taking your first dose early in the morning and another in the late afternoon—these correspond to times when magnesium levels are low in the body. Is it just a coincidence that these times of low magnesium and low energy also correspond to the cultural rituals of morning coffee and afternoon tea?

Loose stools indicate you are not absorbing the magnesium, but that it is acting as a laxative. When the magnesium travels through the intestines in less than twelve hours, it is merely excreted rather than absorbed. If you find you cannot overcome the laxative effect by varying your dosages, you may want to try an oral supplement that is chelated to an amino acid, such as magnesium taurate and magnesium glycinate, which some consider to be better absorbed than the salt forms and less likely to cause loose stools. For those who need a little help with digestion, such as young children, older adults, and anyone with reduced stomach acid or bowel dysbiosis, consider homeopathic magnesium, also referred to as tissue salts or cell salts. Magnesia phosphorica 6X is the appropriate dosage, and it works to usher magnesium into the cells where it belongs. It is also indicated as a remedy for muscle spasms and cramps of many varieties. Mag phos can help reduce and eliminate loose stools while you are supplementing with oral magnesium, giving you a positive sign that your body is indeed taking the magnesium into the cells.

Yet another option for oral magnesium supplementation is ionic magnesium in liquid form, such as that offered by Trace Minerals Research. This is a sodium-reduced concentration of sea water from the Great Salt Lake in Utah. Only about a teaspoon is needed to deliver about 400 milligrams of magnesium (along with seventy-two other trace minerals), which should be taken in divided amounts during the day. I recommend adding this to soups (made with bone-broth bases of course) as the strong mineral taste is hard to take straight. You can also add this to spring and other drinking water to up the magnesium content and use it in cooking. By “micro-dosing” your food and water in this fashion you greatly reduce any laxative effects a large dose of magnesium might elicit.

Another potential way to get more magnesium into your system is via the pleasant method of soaking in a bath of magnesium sulfate, otherwise known as Epsom salts. Commonly used to ease muscle aches and pains, magnesium sulfate also importantly helps with detoxification when sulfur is needed by the body for this purpose. When used intravenously, magnesium sulfate can save lives in such crises as acute asthma attack, onset of myocardial infarction, and eclampsia in pregnancy.

A couple of cups of Epsom salts added to a hot bath will induce sweating and detoxification; after the water cools a bit, the body will then absorb the magnesium sulfate. According to Mark Sircus in Transdermal Magnesium Therapy, the effects from a bath of Epsom salts, although pleasant, are brief as magnesium sulfate is difficult to assimilate and is rapidly lost in the urine. Magnesium chloride, which can also be used in baths, is more easily assimilated and metabolized, and so less is needed for absorption.
Finally, magnesium may be applied topically in a form commonly called magnesium “oil.” This is actually not an oil at all, but a supersaturated concentration of magnesium chloride and water. It does feel oily and slippery when applied to the skin, but it absorbs quickly, leaving a slightly tacky, “sea salt” residue that can be washed off. There are many advantages to transdermal magnesium therapy, since the gastrointestinal tract is avoided altogether and there is no laxative effect. Next to intravenous magnesium administration, transdermal therapy provides a greater amount of magnesium to be absorbed than even the best tolerated oral supplements, and can restore intracellular concentrations in a matter of weeks rather than the months required for oral supplementation.

MISSING LINK?

It is likely safe to say that most people would benefit from an increased supply of magnesium in their diets, especially in these times of so many dietary, environmental, and social stressors. Of course no single nutrient stands alone in relation to the body, and the first priority is to eat a varied diet of whole plant and animal foods from the best sources near you. Adding extra magnesium, however, might be the missing nutritional link to help us guard against heart disease, stroke, depression, osteoporosis and many other disorders. In the prevention and alleviation of these diseases, magnesium can be truly miraculous.

SIDEBARS
THE MANY EFFECTS OF MAGNESIUM DEFICIENCY
• ADD/ADHD
• Alzheimer’s
• Angina pectoris
• Anxiety disorders
• Arrhythmia
• Arthritis—rheumatoid and osteoarthritis
• Asthma
• Autism
• Auto-immune disorders
• Cerebral palsy in children of Mg deficient mothers
• Chronic Fatigue Syndrome
• Congestive Heart Failure • Constipation
• Crooked teeth/narrow jaw in children from Mg deficient mothers
• Dental caries
• Depression
• Diabetes, types I and II
• Eating disorders—bulimia and anorexia
• Fibromyalgia
• Gut disorders including peptic ulcer, Crohn’s disease, colitis
• Heart disease
• Hypertension
• Hypoglycemia
• Insomnia
• Kidney stones
• Lou Gehrig’s disease
• Migraines
• Mitral valve prolapse
• Multiple sclerosis
• Muscle cramping, weakness, fatigue
• Myopia—in children from Mg deficient mothers
• Obesity—especially associated with high carbohydrate diet
• Osteoporosis
• Parkinson’s disease
• PMS—including menstrual pain and irregularities
• PPH (Primary pulmonary hypertension)
• Reynaud’s syndrome
• SIDS (Sudden Infant Death Syndrome)
• Stroke
• Syndrome X
• Thyroid disorders
Source: Primal Body—Primal Mind, by Nora Gedgaudas.

THE MAGNESIUM CONTENT OF MILK

In general, milk is not a rich source of magnesium, but many cultures throughout the ages have depended upon dairy foods as the foundation of balanced, healthy diets that conferred strength and vitality. Weston Price, for example, investigated residents of the Swiss Alps as well as the African Maasai whose sturdy, disease-resistant individuals had little or no tooth decay. But can we can replicate those diets with the same health-giving properties if we depend upon today’s industrialized food model?

The mineral composition of milk depends upon many factors, including the breed of animal, stage of lactation, frequency of milking, environmental conditions, type of pasture, soil makeup and amount of soil contamination. Grass tetany, for instance, is a serious and potentially fatal condition in cattle characterized by extremely low levels of serum magnesium. Also called “grass staggers” or “wheat pasture poisoning,” it is the result of animals grazing on fast-growing young grass in spring or fall on soil that is severely magnesium deficient, as can happen when the pastures have been fertilized with high nitrogen and potassium fertilizers. In acute poisoning, the animal can be saved by injections of magnesium sulfate; yet subclinical magnesium deficiency in the herd may go undetected.

By contrast, pastures that offer a great deal of plant diversity to grazing animals also offer diversity to the soil ecology as well as nutrient diversity to the ruminant. In a Swiss study that examined thirty plant species of alpine pastures, researchers found that “the botanical composition of an alpine pasture has a significant influence on the nutritive value of the forage…. Compared with grass species, legumes and herbs showed a lower content of cell walls but a higher content of crude protein, as well as four times the content of calcium and twice the content of magnesium.” The Swiss visited by Dr. Price grazed their cattle on alpine slopes populated by numerous plant species and watered by the mineral-rich glacial run-off—water the villagers also used in drinking and cooking.

Numerous stresses can take their nutritional toll on the dairy animal and therefore on the quality of her milk. Crowding, confinement, filth and unnatural fodder come to mind instantly as obvious offenders, but too frequent milking— more than once a day—can result in dilution of nutrients in the milk. The daily output is greater, but the nutrients are fewer by volume.

“The mineral content of milk and popular meats has fallen significantly in the past 60 years, according to a new analysis of government records of the chemical composition of everyday food,” begins an article in the Guardian about researcher David Thomas’s comparison of food tables from 1940 and 2002. The research was done for the consumer watchdog group in the UK, the Food Commission, and published in their quarterly journal, The Food Magazine. Mineral declines in dairy products showed that milk lost 60 percent of its iron, 2 percent of its calcium, and 21 percent of its magnesium. Compared to 1940, currently “[m]ost cheeses showed a fall in magnesium and calcium levels. According to the analysis, cheddar provides 9 percent less calcium today, 38 percent less magnesium and 47 percent less iron, while parmesan shows the steepest drop in nutrients, with magnesium levels down by 70 percent.”

Ignoring the declining magnesium content in foods such as dairy products may have confounded some analyses of disease etiology in large populations. Anti-animal-fat proponents tend to blame the rampant incidence of heart disease among the Finns on their high intakes of dairy products.

However, according to Dr. Mildred Seelig, of New York University Medical Center, “In Finland, which has a very high death rate from IHD (ischemic heart disease), there is a clear relationship with heart disease and the amount of magnesium in the soil. In eastern and northern Finland, where the soil content is about a third of that found in southwestern Finland, the mortality from ischemic heart disease is twice as high as is that in the southwest. Ho and Khun surveyed factors that might be contributory both to the rising incidence of cardiovascular disease in Europe, and the falling levels of magnesium both in the soil and in the food supply. They commented that in Finland, which has the highest cardiovascular death rate in Europe, the dietary supply of magnesium has decreased by 1963 to a third of the intake common in 1911.”

Modern, urban Finns of course consume pasteurized dairy products, which not only have reduced magnesium levels to begin with thanks to modern farming practices, but also have less soluble calcium as a result of the denaturing of the enzyme phosphatase during pasteurization. Calcium that is not soluble precipitates out to soft tissue, such as the vascular system, and can contribute to a cascade of ominous events linked to heart disease.

We might surmise from these observations, then, that dairy products must be produced with reverence not only to the beast herself, but also to the soil that feeds the pasture that feeds her. When all nutrients are in balance with one another we can expect the food to have the power to truly nourish us.

Countless stressors in life today increase the body’s demands for magnesium—by our challenged endocrine systems, by environmental poisons that must be neutralized, by excess refined carbohydrates in our diets, to name a few. The balance of nutrients provided in the foods in the groups that Dr. Price visited was also in felicitous balance with those peoples’ physical, emotional, and social ecologies. We can only strive, both as consumers and producers of food, to achieve that equilibrium in the ecologies we inhabit.

FOOD SOURCES OF MAGNESIUM

In milligrams per 100 grams
Kelp760Pecan142Beets25
Wheat bran490Walnut131Broccoli24
Wheat germ336Rye115Cauliflower24
Almonds270Tofu curdled by Mg nigiri111Carrot23
Cashews267Coconut meat, dried90Celery22
Blackstrap molasses258Collard greens57Beef21
Nutritional yeast231Shrimp51Asparagus20
Buckwheat229Corn, sweet48Chicken19
Brazil nuts225Avocado45Green pepper18
Dulse220Cheddar cheese45Winter squash17
Filberts184Parsley41Cantaloupe16
Peanuts175Prunes40Eggplant16
Millet162Sunflower seeds38Tomato14
Wheat whole grain160Sweet potato31Milk
13
MAGNESIUM SUPPLEMENTATION CAN BE TRICKY

Even when it seems obvious that magnesium supplementation is called for to alleviate typical deficiency symptoms such as anxiety or heart palpitations, finding the best means to raise intracellular levels can be difficult. Most often, oral supplements will cause laxative effects at levels too low to restore magnesium supplies to the cells, where it is needed. Marina, whose husband Alex was recovering from heart surgery, had to be persistent. “I noticed in the hospital that he was given intravenous magnesium during intensive care, but the doctors never mentioned it later on, when Alex was overcome with panic attacks, bouts of low energy, hypertension and arrhythmia. We were offered drugs for all of these conditions, but we both wanted to avoid the medications if at all possible, although we couldn’t at first. A couple of alternative doctors had mentioned magnesium along with other supplements that could help, but with no particular emphasis on the magnesium, so it was by trial and error that we discovered just how effective the magnesium could be. But first we had to find the best way for Alex to take it.

“Capsules of magnesium citrate and magnesium taurate both caused diarrhea at only a quarter of the recommended dose. I learned that chronic magnesium deficiency can unfortunately leave you with a much reduced capacity for intestinal absorption, and it was likely that Alex had been deficient for a long time. This was hard for me to accept at first, since he had been eating a superb diet for many years—full of mineral-rich bone broths, soups with seaweeds and nettles, and no sugar or caffeine.

But his history included decades of intense stress and obvious signs of adrenal exhaustion.

“I next tried liquid ionic magnesium, which included trace minerals as found in the Great Salt Lake in Utah. I felt that magnesium in isolation might not be the best way to try to absorb it. Starting with just a few drops in his soup, Alex was able to take more magnesium over time in this fashion, although we still had to be very careful not to exceed a certain amount or the diarrhea would return. Nevertheless, we were starting to see positive results. First came better sleep. Alex had been waking every ninety minutes during the night—he’d get up to pee, come back to bed and struggle to fall asleep only to wake again in ninety minutes to repeat the process. He was certain his prostate was failing, but after about a month with the ionic magnesium, he was able to sleep uninterrupted for three-, then four-, then six-hour spans. We realized his prostate was fine, but his traumatized adrenals had been regularly firing an adrenaline rush to jolt him awake. When they began to be pacified his sleep finally became restful; he now usually only wakes once during the night and can easily return to sleep. And, dare I say, he sleeps better these days than he has for years. Also, with a good night’s sleep his daytime energy level is much improved.

“Alex still had bouts of arrhythmia which had been very frightening at times, and although his hypertension was improving with energy work and flower essences, we knew there was a nutritional component that needed to be addressed. A friend happened to suggest using homeopathic magnesium to help with absorption—she herself was starting to use magnesium supplements and was also experiencing the common problem of loose stools when this solution dawned on her. The concept was brilliant—we needed a way to gently get the cells to accept the magnesium, and so we began using the tissue salts Magnesia phosphorica in the 6X potency. After the very first dose Alex had improvement with his stool and was able to keep up the same dosage of the ionic magnesium. It was as though a key had opened a lock, and the magnesium was now entering the cells where it could do its good.

“One day Alex casually mentioned that he hadn’t had a single moment of arrhythmia in a week. This was stunning news, since he had had at least slight arrhythmia daily for months. Everyone told us this was extremely common after heart surgery and we thought we’d have to accept this fact. Encouraged by his progress, I next purchased some magnesium ‘oil’ in order to have yet another means to deliver the magnesium without involving the intestinal tract at all.

“Our current protocol includes a once-daily use of the magnesium oil. I add ionic magnesium drops to our drinking and cooking water, as well as to every pot of soup, pan of sautéed vegetables, tray of stuffed peppers. I call this ‘microdosing’ and it is in addition to using sea vegetables and plenty of bone broths. Along with the Magnesia phosphorica, Alex takes the tissue salt Kali phosphorica (potassium phosphate) which is indicated for all conditions of nervous debility; the two together make a very good heart tonic. At bedtime, Alex has a single dose of magnesium citrate with a food complex vitamin C powder. This is a relaxing evening ritual and now causes no intestinal upset.

“The only medication Alex still takes is a beta-blocker for hypertension—a small dose that we hope to be able to quit soon. If you supplement with magnesium and have hypertension you will need to pay close attention to your blood pressure. You will have to reduce your medication accordingly or your blood pressure could get too low too fast! You must do this slowly, though, to give the vascular tissue time to recondition itself and regain elasticity—as it will.

“Finally, Alex himself wanted me to add that the magnesium therapy allowed him to shift the intensity of his focus from his physical condition to his spiritual life, and sparked new creativity. He has begun to write and will be publishing the first in a series of his memoirs early next year. Truly, who would have thought so much healing could be initiated by finally replenishing this neglected mineral?”

REFERENCES
The Magnesium Miracle, by Carolyn Dean, M.D., N.D., Ballantine Books, 2007.
Transdermal Magnesium Therapy, by Mark Sircus, Ac., O.M.D., Phaelos Books, 2007.
Magnesium Therapy, by Patricia Ann Braun, M.D. http:// pbraunmd.org/magnesium.htm.
Magnesium: The Nutrient that Could Change Your Life, by J.I. Rodale http://www.mgwater.com/rod06.shtml.
Leaky gut and magnesium deficiency: http://magnesiumforlife.com/medical-application/magnesium-and-autism/.
The dangers of magnesium deficiency in endurance athletes: http://findarticles.com/p/articles/mi_m0FDL/is_4_14/ai_n24940334/.
Primal Body-Primal Mind, by Nora Gedgaudas, Primal Body-Primal Mind Publishing, 2009.
Healing Wise: Wise Woman Herbal, by Susun S. Weed, Ash Tree Publishing, 1989.
Put Your Heart in Your Mouth, by Dr. Natasha Campbell- McBride, Medinform, 2007.

This article appeared in Wise Traditions in Food, Farming and the Healing Arts, the quarterly magazine of the Weston A. Price Foundation, Fall 2010.
About the Author
Katherine Czapp
Katherine Czapp was raised on a three-generation, self-sufficient mixed family farm in rural Michigan. After studying Russian language and literature at the University of Michigan, she is gratified to discover that the skills and experiences of her anachronistic upbringing are useful tools in the 21st century. She works independently as a three-season organic gardener and WAPF staff editor. She and her husband Garrick live the slow life in Ann Arbor, Michigan. To learn more about authentic sourdough bread recipes and to obtain a live culture starter, visit www.realsourdoughbreadrecipe.com.

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Read the complete article here.

Friday, April 1, 2011

Is Your Bottled Water Killing You

Is Your Bottled Water Killing You?


By William Davis, MD

Health Benefits of Magnesium Replacement

What can you expect from supplementing magnesium to optimal levels? Research over the past 20 years suggests that magnesium supplementation will accomplish several critically important goals:
  • Magnesium improves insulin sensitivity. Magnesium helps correct impaired insulin sensitivity, the fundamental defect that characterizes pre-diabetes and metabolic syndrome. An intracellular enzyme called tyrosine kinase requires magnesium to allow insulin to exert its blood-sugar-lowering effects. In several studies, daily oral magnesium supplementation substantially improved insulin sensitivity by 10% and reduced blood sugar by 37%.21-23
  • Magnesium helps correct abnormal lipoprotein patterns. Improved insulin sensitivity from magnesium replacement can markedly reduce triglyceride levels.23 Reduced triglyceride availability, in turn, reduces triglyceride-rich particles, such as very low-density lipoprotein (VLDL) and small low-density lipoprotein (small LDL), both of which are powerful contributors to heart disease.24 Magnesium supplementation can also raise levels of beneficial high-density lipoprotein (HDL).24
  • Magnesium suppresses abnormal heart rhythms. Magnesium has gained a foothold in hospital care following coronary bypass surgery, when the abnormal heart rhythm known as atrial fibrillation commonly occurs. Magnesium may help suppress this rhythm outside of the hospital as well,25 suggesting a preventive role in averting abnormal heart rhythms.
  • Magnesium reduces blood pressure. Magnesium regulates blood pressure by modulating vascular tone. Magnesium works in ways similar to the prescription hypertension drugs known as calcium-channel antagonists (such as diltiazem and nifedipine), which block calcium channels that trigger constriction of the arteries. Magnesium stimulates the production of prostacyclins and nitric oxide, which are potent artery-relaxing agents.26 Magnesium exerts a modest effect of reducing blood pressure, reflecting its whole-body artery-relaxing properties.27
  • Magnesium can block migraine headaches. Magnesium has been explored as a means to prevent or relieve migraine headaches. People suffering migraine headaches tend to have lower magnesium levels.28 A study from the State University of New York showed that intravenous magnesium relieved headache symptoms in 15 minutes in 80% of recipients.29 Other studies have since corroborated magnesium’s beneficial effect on migraine headaches, including a trial in children, in which oral supplementation with magnesium oxide reduced the frequency and severity of migraine.30
  • Magnesium may improve exercise performance. Extensive research in athletes has found that intensive exercise triggers magnesium loss through urinary excretion and perspiration. When magnesium is low, supplementation enhances exercise performance by reducing lactate blood levels (indicating brief, strength-based anaerobic muscle activity), decreasing oxygen requirements, and increasing muscle strength.31,32
  • Magnesium may benefit many other conditions. Other conditions in which magnesium is believed to exert positive effects include fibromyalgia,33 asthma (acute episodes have been treated successfully with both intravenous and aerosolized magnesium),34 prevention of osteoporosis,35 and premenstrual syndrome.36
Can you correct metabolic syndrome and its complications—such as insulin resistance and high blood pressure—without replacing magnesium? Of course you can, just as you can operate your car without changing the oil. However, magnesium deficiency will catch up with you, and consuming this basic supplement will help you to more easily achieve your health goals.

Strategies for Optimizing Your Magnesium Intake

According to the US Department of Health and Human Services, nearly all of us fail to achieve even the modest magnesium RDAs of 420 mg for adult males and 320 mg for adult females. Most American adults ingest about 270 mg of magnesium a day, well below the RDA and enough to generate a substantial cumulative deficiency over months and years.37
The magnesium RDA refers to elemental magnesium, defined as the amount of magnesium regardless of its source or form. Magnesium is generally available as various “salts” (not to be confused with table salt), and the amount of elemental magnesium contained in each varies depending on the salt. For example, the amount of magnesium in magnesium oxide is 60%; in magnesium carbonate, 45%; in magnesium citrate, 16%; and in magnesium chloride, 12%.38 Thus, magnesium oxide supplements tend to contain more elemental magnesium per pill than do magnesium citrate supplements.
Magnesium salts differ in absorption. Magnesium oxide, though inexpensive and widely available, is thought to be relatively less absorbed than the citrate and chloride forms.39-41
You can also increase your magnesium intake by choosing foods rich in magnesium, which are listed in the table below.42
Foods rich in magnesium (magnesium content in mg)
Almonds (1 oz; 24 nuts) 78Oatmeal (1 cup, cooked) 56
Artichokes (1 cup) 101Pumpkin seeds (1 oz; 142 seeds) 151
Barley (1 cup, raw) 158Rice, brown (1 cup, cooked) 84
Beans, black (1 cup, cooked) 120Soybeans (1 cup, cooked)148
Beans, lima (1 cup, cooked) 101Spinach (1 cup, cooked) 163
Brazil nuts (1 oz; 6-8 nuts)107Trail mix (1 cup) 235
Halibut (1/2 filet) 170Walnuts (1 oz; 14 halves) 45
Filberts, hazelnuts (1 oz) 46Wheat flour, whole grain (1 cup) 166
Oat bran (1 cup, raw) 221Source: USDA National Nutrient database for Standard Reference, Release17

Dietary Sources of Magnesium

Nuts, pumpkin seeds, spinach, and oat bran are particularly rich and healthy sources of magnesium.
Another strategy for boosting magnesium intake is to supplement your diet with the soluble fiber known as inulin. Like other soluble fibers, inulin may exert modest cholesterol- and triglyceride-reducing effects. However, it also enhances magnesium absorption in the intestine.43 Inulin can be taken as a supplement, and is contained in some foods (for example, the Stonyfield Farms brand of yogurt). Inulin can help increase satiety (the sense of fullness you get with eating), resulting in decreased calorie intake throughout the day.44 Inulin thus holds promise in supporting efforts to lose weight.45
One more important way to optimize your magnesium intake is to choose water that is rich in magnesium. Unfortunately, in the US, this is easier said than done. The FDA regulates bottled water and mandates that the only additives permitted are fluoride and antimicrobials to deter bacterial growth. Magnesium cannot therefore be added to water labeled spring water or mineral water.
Magnesium Content of Mineral Waters
The following waters contain far more than the usual amounts of magnesium. Some, like Apollinaris and Pellegrino, are widely available in American grocery stores, while others are found only in upscale groceries or through websites of the water producers.
Mineral WaterMagnesium Content
Original Fountain of Youth Mineral Water (Florida) 609 mg/L
Apollinaris (Germany) (410 mg/L of sodium)130 mg/L
Adobe Springs (California and other western states) 110 mg/L
Badoit (France)85 mg/L
Colfax (Iowa)91 mg/L
Deep Rock (Colorado) 60 mg/L
Evian 24 mg/L
Gerolsteiner (Germany)108 mg/L
Noah’s California Spring Water 110 mg/L
Pellegrino Sparkling Mineral Water (Italy) (43.6 mg/L of sodium) 55.9 mg/L
Manitou Mineral Water (Colorado) 43 mg/L
Rosbacher 93 mg/L
St. Gero109.4 mg/L
Both Apollinaris and Pellegrino contain more sodium than most other waters, and therefore should be avoided by those who are limiting their sodium intake due to existing hypertension, fluid retention, or kidney disease.
Magnesium-rich mineral waters are not easy to find, but they are out there. By FDA definition, mineral waters must contain at least 250 parts per million (ppm) of total dissolved solids. Not all mineral water contains significant quantities of magnesium. For example, Napa Valley’s Calistoga Springs, labeled as “mineral water,” contains 0.61–0.96 mg/L of magnesium, or virtually none.
Magnesium Dosage Guidelines
  • The recommended dietary allowance (RDA) for magnesium is 420 mg a day for adult men and 320 mg a day for adult women.46 Most people fail to achieve the RDA, which may lead to magnesium deficiency.37
  • The most common adverse reaction from the use of magnesium supplements is diarrhea. Other gastrointestinal symptoms include nausea and abdominal cramping. Diarrhea and other gastrointestinal symptoms are less likely to occur if magnesium supplements are taken with food.46
  • Magnesium supplements are contraindicated in those with kidney failure. Those with myasthenia gravis (an autoimmune disorder that results in progressive skeletal muscle weakness) should avoid magnesium supplements.46
To determine the amount of magnesium contained in bottled water labeled “mineral water” but not listed above, go to the bottler’s website to determine the water’s composition.
With the exception of Florida’s Original Fountain of Youth Mineral Water, drinking an entire liter of many so-called mineral waters provides only a modest amount of magnesium. Thus, for instance, if you are currently ingesting around 250 mg a day of magnesium from your diet, drinking a liter of Gerolsteiner a day (supplying 108 mg/L of magnesium) will increase your magnesium consumption only to about 350 mg per day. However, by adding a magnesium supplement that provides as little as 100 mg of elemental magnesium, you will have more than achieved the RDA for an adult male. Since many mineral waters are expensive (around $2-3 per liter), magnesium supplements are a far less costly way to optimize your magnesium intake.

Conclusion

The intensification of municipal water treatment has resulted in a growing epidemic of magnesium deficiency, with most Americans failing even to achieve the modest levels set by the government-recommended RDA. Most of us have daily deficiencies in magnesium intake of only 70-200 mg a day.
The consequences of magnesium deficiency can be dramatic, including poor insulin response, migraine headaches, high blood pressure, and abnormal and even dangerous heart rhythms.
Fortunately, there are plenty of healthy choices—foods rich in magnesium, low-cost magnesium supplements, and waters rich in magnesium—that can you help reach or exceed the magnesium RDA and attain the numerous health benefits conferred by optimal magnesium intake.
Dr. William Davis is an author and cardiologist practicing in Milwaukee, WI. He is founder of the Track Your Plaque program, a heart disease prevention and reversal program that shows how CT heart scans can be used to track and control coronary plaque. He can be reached at www.TrackYourPlaque.com.
The Basics of Water and Water Purification
While the Environmental Protection Agency regulates the quality of tap water, the Food and Drug Administration (FDA) is responsible for regulating bottled water. In 1995, the FDA issued its most recent regulations classifying various waters:
  • Artesian well water is water that naturally flows upward from an underground aquifer to a well, without the need for pumping.
  • Mineral water is water from an underground source that contains at least 250 parts per million (ppm) of dissolved solids consisting of minerals and trace elements. Mineral content of 250-500 ppm is often called “low mineral content” or “light mineral water,” while content of 1500 ppm or greater is “high mineral content.” (In Europe, spring waters with dissolved solids equal to or less than 500 mg/L are considered “mineral with low mineral content” or simply “mineral water.”) Minerals and trace elements cannot be added artificially to water labeled as mineral.
  • Spring water, like artesian well water, comes from an underground source but flows naturally to the earth’s surface. It cannot come from a public or municipal source. Spring water must be collected directly at the spring or through a borehole tapping the underground source. Mineral content is less than 250 ppm and cannot be added after collection.
  • Well water is water from a hole bored or drilled into the ground, which taps into an aquifer and is drawn to the surface using a pump. Many homes in the US that do not have access to municipal water use well water.
To make matters even more complicated, any water—regardless of the source—can be treated or filtered. This is usually done to modify its taste or to remove undesirable ingredients. Methods of treatment are defined as:
  • Distillation. Water is vaporized and collected, leaving behind any solid residues, including minerals. Distilled water contains no minerals whatsoever.
  • Reverse osmosis. In this common water-purifying process, water is forced through membranes to remove minerals in the water.
  • Deionization. Also called demineralization or ion exchange, this process uses synthetic resins to remove ions and minerals from water. This is very effective at removing ionized impurities, but does not remove organic, bacterial, pathogenic, or particulate matter efficiently. Deionized water contains no magnesium.
  • Absolute 1 micron filtration. Water is passed through filters that remove particles larger than 1 micron in size, including Cryptosporidium, a parasite that causes intestinal infestation. This process does not affect the water’s mineral content.
  • Ozonation. Many bottled water companies use this process instead of chlorine to rid water of bacteria. Ozonation does not affect the mineral content of water.
Many bottled waters are simply tap water processed using one or more of the above processes of distillation, reverse osmosis, deionization, or filtration. This leaves the water virtually devoid of both nutrients and contaminants. Of the 700 or so brands of bottled water available in the US, 80% are processed water. Many experts say that treated water like this is virtually identical to that produced by home water purifiers. The appeal of these waters is therefore a reduction in impurities like lead and pesticide residues, or better taste—but not enhanced mineral content. Bottled processed waters contain little or no magnesium.
It should also be noted that unlike tap water, purified waters and water purifiers reduce or eliminate the fluoride that is added by many municipal treatment facilities to promote dental health. Although the FDA permits producers to add it back to purified water, few actually do.
Waters derived from natural sources like artesian well water, well water, mineral water, and spring water are generally slightly richer in mineral content than are processed and tap waters. However, the difference is small. Nearly all American bottled waters obtained from natural sources—whether artesian, well, spring, or mineral waters—contain less than 6 ppm of magnesium, a trivial amount.
References
1. Available at: http://www.historyofwaterfilters.com/. Accessed November 14, 2006.
2. Azoulay A, Garzon P, Eisenberg MJ. Comparison of the mineral content of tap water and bottled waters. J Gen Intern Med. 2001 Mar;16(3):168-75.
3. Available at: http://lpi.oregonstate.edu/infocenter/minerals/magnesium/index.html. Accessed November 14, 2006.
4. Touyz RM. Magnesium in clinical medicine. Front Biosci. 2004 May 1;9:1278-93.
5. Liebscher DH, Liebscher DE. About the misdiagnosis of magnesium deficiency. J Am Coll Nutr. 2004 Dec;23(6):730S-1S.
6. Durlach J, Bac P, Durlach V, et al. Magnesium status and ageing: an update. Magnes Res. 1998 Mar;11(1):25-42.
7. Eisenberg MJ. Magnesium deficiency and sudden death. Am Heart J. 1992 Aug;124(2):544-9.
8. Dacey MJ. Hypomagnesemic disorders. Crit Care Clin. 2001 Jan;17(1):155-73, viii.
9. Eisenberg MJ. Magnesium deficiency and cardiac arrhythmias. NY State J Med. 1986 Mar;86(3):133-6.
10. Purvis JR, Movahed A. Magnesium disorders and cardiovascular diseases. Clin Cardiol. 1992 Aug;15(8):556-68.
11. Smetana R, Stuhlinger HG, Kiss K, Glogar DH. Intravenous magnesium sulphate in acute myocardial infarction—is the answer “MAGIC”? Magnes Res. 2003 Mar;16(1):65-9.
12. Kousa A, Havulinna AS, Moltchanova E, et al. Calcium:magnesium ratio in local groundwater and incidence of acute myocardial infarction among males in rural Finland. Environ Health Perspect. 2006 May;114(5):730-4.
13. Anderson TW, Le Riche WH, MacKay JS. Sudden death and ischemic heart disease. Correlation with hardness of local water supply. N Engl J Med. 1969 Apr 10;280(15):805-7.
14. Available at:http://www.nsf.org/international/press_release.asp?p_id=12041. Accessed November 14, 2006.
15. Laires MJ, Monteiro CP, Bicho M. Role of cellular magnesium in health and human disease. Front Biosci. 2004 Jan 1;9:262-76.
16. Berkelhammer C, Bear RA. A clinical approach to common electrolyte problems: 4. Hypomagnesemia. Can Med Assoc J. 1985 Feb 15;132(4):360-8.
17. Roffe C, Sills S, Crome P, Jones P. Randomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps. Med Sci Monit. 2002 May;8(5):CR326-30.
18. Bilbey DL, Prabhakaran VM. Muscle cramps and magnesium deficiency: case reports. Can Fam Physician. 1996 Jul;42:1348-51.
19. Bussone G. Pathophysiology of migraine. Neurol Sci. 2004 Oct;25 Suppl 3S239-41.
20. He K, Liu K, Daviglus ML, et al. Magnesium intake and incidence of metabolic syndrome among young adults. Circulation. 2006 Apr 4;113(13):1675-82.
21. Guerrero-Romero F, Tamez-Perez HE, Gonzalez-Gonzalez G et al. Oral magnesium supplementation improves insulin sensitivity in non-diabetic subjects with insulin resistance. A double-blind placebo-controlled randomized trial. Diabetes Metab. 2004 Jun;30(3):253-8.
22. Rodriguez-Moran M and Guerrero-Romero F. Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects: a randomized double-blind controlled trial. Diabetes Care. 2003 Apr;26(4):1147-52.
23. Yokota K, Kato M, Lister F, et al. Clinical efficacy of magnesium supplementation in patients with type 2 diabetes. J Am Coll Nutr. 2004 Oct;23(5):506S-9S.
24. Rasmussen HS, Aurup P, Goldstein K, et al. Influence of magnesium substitution therapy on blood lipid composition in patients with ischemic heart disease. A double-blind, placebo controlled study. Arch Intern Med. 1989 May;149(5):1050-3.
25. Piotrowski AA, Kalus JS. Magnesium for the treatment and prevention of atrial tachyarrhythmias. Pharmacotherapy. 2004 Jul;24(7):879-95.
26. Sontia B, Touyz RM. Role of magnesium in hypertension. Arch Biochem Biophys. 2006 May 24.
27. Jee SH, Miller ER, III, Guallar E, et al. The effect of magnesium supplementation on blood pressure: a meta-analysis of randomized clinical trials. Am J Hypertens. 2002 Aug;15(8):691-6.
28. Gallai V, Sarchielli P, Morucci P, Abbritti G. Magnesium content of mononuclear blood cells in migraine patients. Headache. 1994 Mar;34(3):160-5.
29. Mauskop A, Altura BT, Cracco RQ, Altura BM. Intravenous magnesium sulfate rapidly alleviates headaches of various types. Headache. 1996 Mar;36(3):154-60.
30. Wang F, Van Den Eeden SK, Ackerson LM, et al. Oral magnesium oxide prophylaxis of frequent migrainous headache in children: a randomized, double-blind, placebo-controlled trial. Headache. 2003 Jun;43(6):601-10.
31. Lukaski HC. Magnesium, zinc, and chromium nutrition and athletic performance. Can J Appl Physiol. 2001;26 SupplS13-S22.
32. Cinar V, Nizamlioglu M, Mogulkoc R. The effect of magnesium supplementation on lactate levels of sportsmen and sedanter. Acta Physiol Hung. 2006 Jun;93(2-3):137-44.
33. Sarac AJ, Gur A. Complementary and alternative medical therapies in fibromyalgia. Curr Pharm Des. 2006;12(1):47-57.
34. Blitz M, Blitz S, Hughes R, et al. Aerosolized magnesium sulfate for acute asthma: a systematic review. Chest. 2005 Jul;128(1):337-44.
35. Rude RK, Gruber HE. Magnesium deficiency and osteoporosis: animal and human observations. J Nutr Biochem. 2004 Dec;15(12):710-6.
36. Rapkin A. A review of treatment of premenstrual syndrome and premenstrual dysphoric disorder. Psychoneuroendocrinology. 2003 Aug;28 Suppl 3:39-53.
37. Ervin RB, Wang CY, Wright JD, Kennedy-Stephenson J. Dietary intake of selected minerals for the United States population: 1999-2000. Adv Data. 2004 Apr 27;(341):1-5.
38. Available at: http://ods.od.nih.gov/factsheets/magnesium.asp#h6. Accessed November 15, 2006.
39. Firoz M, Graber M. Bioavailability of US commercial magnesium preparations. Magnes Res. 2001 Dec;14(4):257-62.
40. Coudray C, Rambeau M, Feillet-Coudray C, et al. Study of magnesium bioavailability from ten organic and inorganic Mg salts in Mg-depleted rats using a stable isotope approach. Magnes Res. 2005 Dec;18(4):215-23.
41. Walker AF, Marakis G, Christie S, Byng M. Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study. Magnes Res. 2003 Sep;16(3):183-91.
42. Available at: http://www.nal.usda.gov/fnic/foodcomp/Data/SR14/wtrank/sr14w304.pdf. Accessed November 15, 2006.
43. Roberfroid MB. Introducing inulin-type fructans. Br J Nutr. 2005 Apr; 93 Suppl 1S13-S25.
44. Archer BJ, Johnson SK, Devereux HM, Baxter AL. Effect of fat replacement by inulin or lupin-kernel fibre on sausage patty acceptability, post-meal perceptions of satiety and food intake in men. Br J Nutr. 2004 Apr;91(4):591-9.
45. Hoeger WW, Harris C, Long EM, Hopkins DR. Four-week supplementation with a natural dietary compound produces favorable changes in body composition. Adv Ther. 1998 Sep-Oct;15(5):305-14.
46. Available at: http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/mag_0167.shtml. Accessed November 16, 2006.

Magnesium

Written By:  William Davis, MD       

February is Heart Health Month and heart health expert and cardiologist Dr. William Davis, M.D., talks about the importance of lowering high cholesterol naturally and reducing your chances of coronary heart disease with the use of magnesium and other nutritional strategies.

Tired of the media onslaught promoting statin drugs? What happened to the conversation about nutritional strategies that reduce cholesterol? Since February is Heart Health Month, now is a great time to highlight the importance of magnesium for the reduction of high cholesterol.

There are a number of ways to significantly reduce cholesterol using diet and nutritional supplements. Reductions in bad cholesterol, or LDL cholesterol, of 25, 30, 50, even 100 mg/dl are possible—if you have the right information.

At the top of the list of natural strategies to reduce LDL and supplement and/or sometimes replace your need for prescription medication (in consultation with your doctor) is magnesium.
Magnesium can act like a natural statin drug and lower bad cholesterol (LDL), reduce triglycerides and increase good cholesterol (HDL) (1).

In order for the body to make cholesterol, it requires a specific enzyme called HMG-CoA reductase. Magnesium regulates this enzyme so as to maintain only a proper amount of cholesterol in the body. When the body is magnesium deficient, cholesterol continues to be produced in excess, which can cause a cholesterol buildup and may lead to coronary heart disease.

The HMG-CoA reductase enzyme is the exact same enzyme that is targeted and inhibited by statin drugs. The inhibiting process is similar to magnesium's function, except that magnesium is the natural way that the body has evolved to use to control and limit cholesterol when it reaches a certain level; statin drugs are used to destroy the entire mechanism.

The term metabolic syndrome describes a set of conditions that many believe may be another name for the consequences of long-term magnesium deficiency. The list includes high cholesterol, hypertension and elevated triglycerides that lead to and promote coronary heart disease, stroke and type-2 diabetes. In a 2006 study (2) published in the American Heart Association's journal Circulation, entitled: Magnesium Intake and Incidence of Metabolic Syndrome Among Young Adults researchers concluded: “Our findings suggest that young adults with higher magnesium intake have lower risk of development of metabolic syndrome.”

In an age when statins dominate conventional heart disease prevention, an important role remains for nutritional approaches. Because statin drugs are principally LDL-reducing agents and do not address other causes of heart disease, nutritional strategies add a real advantage. Nutritional approaches can be used to minimize and sometimes eliminate the use of statin drugs altogether. Perhaps it would be better to regard statin therapy as a solution only when natural, nutritional means have been exhausted.

The adherence to a healthy diet is not enough in the majority of cases. The American Heart Association’s diet, for instance, yields a 7% drop in cholesterol. That’s too small to make any real difference (3) and, by itself, virtually guarantees a future of heart disease. The formerly popular ultra low-fat diets (≤10% of calories from fat) yield variable drops in cholesterol, but HDL or the good cholesterol is also substantially reduced and harmful triglycerides increased (4). The net effect can be increased risk of heart disease and diabetes.

The restriction of processed carbohydrates is an effective way to lose weight and thereby reduce cholesterol, particularly for people starting with lower HDL and higher triglycerides. Reducing intake of flour products (pasta, breads, bagels, pastries, cookies, cakes, pretzels, and other processed foods) may, in fact, yield larger drops in cholesterol than now outdated low-fat diets (5).
While dietary restriction of total fat intake has only limited power to reduce cholesterol, avoidance of saturated fat (e.g., in butter, greasy meats, cured meats, fried foods) and hydrogenated fat (“trans fats” in margarine, shortening, and many processed foods) remains a well-proven means of reducing LDL cholesterol modestly. Replacing saturated fat sources with healthy monounsaturated oils (olive, canola, flaxseed) provides even greater benefits for cholesterol reduction, as well as reduced triglycerides and VLDL (6, CM Williams, et al., 1999).

Weight loss (if you’re overweight) has broad effects on risk reduction: reduction of cholesterol levels (total and LDL), increased HDL, reduced triglycerides, and correction of small LDL, VLDL, and abnormal postprandial (after-eating) fat clearance (7).

Magnesium can help. Magnesium helps the body digest, absorb, and utilize proteins, fats, and carbohydrates and helps prevent obesity genes from expressing themselves.

As a practical solution, supplementation at a level of 2.3 milligrams of magnesium per pound of body weight per day (this comes to about 345 milligrams per day for a 150 lb individual) can really help. When supplementing with magnesium, start on a gradient of a low dose and gradually build up. If you get diarrhea you can lower the dose back down until you are at a comfortable level. While magnesium supplementation is generally quite safe, people on certain antibiotics should not take magnesium. If you have kidney disease (renal failure) or any kidney disorders, you should not take any magnesium supplements without consulting a physician.

In all practicality, because of magnesium’s crucial role in health, its widespread deficiency in Americans, and the growing depletion of magnesium in water and foods, supplemental magnesium is necessary for nearly everyone to ensure healthy levels. Not all forms of magnesium are equally absorbed by the body. One of the most absorbable forms of nutritional magnesium is magnesium citrate in powder form. Start out slow and build up to and find your body's tolerance level.

For most people, no single supplement or diet change will reduce LDL to your target. A combination of several strategies usually yields the large drops that we need to achieve dramatic LDL reduction, but nutritional magnesium and the above diet adjustments will help.

Heart health expert and cardiologist, William Davis, M.D., is the author  of "Track Your Plaque: The only heart disease prevention program that  shows how the new CT heart scans can be used to detect, track, and  control coronary plaque" (www.trackyourplaque.com). Dr. Davis is a  member of the Nutritional Magnesium Association and invites you to get  more information that will help you avoid the magnesium deficiency. Go  to www.nutritionalmagnesium.org.

The ideas, procedures and suggestions contained in this article are not intended as a substitute for consulting with your physician. All matters regarding your physical health require medical supervision. Neither the author nor the publisher shall be liable or responsible for any loss, injury or damage allegedly arising from any information or suggestion in this article. The opinions expressed in this article represent the personal views of the author and not the publisher.
References
  1. Rosanoff A, Seelig MS, “Comparison of mechanism and functional effects of magnesium and statin pharmaceuticals.” J Am Coll Nutr 2004;23(5):501S-505S.
  2. Ka He, MD, ScD; Kiang Liu, PhD; Martha L. Daviglus, MD, PhD et al. Magnesium Intake and Incidence of Metabolic Syndrome Among Young Adults. Circulation 2006;113:1675-1682.
  3. Pearson TA, Blair SN, Daniels SR, Eckel RH, Fair JM, Fortmann SP, et al. AHA guidelines for primary prevention of cardiovascular disease and stroke: 2002 update. Consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases. Circulation 2002;106:388–91.
  4. Krauss RM, Dreon DM. Low-density lipoprotein subclasses and response to a low-fat diet in healthy men. Am J. Clin Nutr 1995: 62:478S–87S.
  5. Krauss RM, Blanche PJ, Rawlings RS, Fernstrom HS, Williams PT. Separate effects of reduced carbohydrate intake and weight loss on atherogenic dyslipidemia. Am J Clin Nutr 2006 May;83(5):1025–31.
  6. Gulesserian T, Widhalm K. Effect of a rapeseed oil substituting diet on serum lipids and lipoproteins in children and adolescents with familial hypercholesterolemia. J Am Coll Nutr 2002 Apr;21(2):103–8.
  7. Miller WM, Nori-Janosz KE, Lillystone M, Yanez J, McCullough PA. Obesity and Lipids. Curr Cardiol Rep 2005 Nov;7(6):465–70.
Published online, Feb. 2010, WholeFoods Magazine
http://www.wholefoodsmagazineonline.com/